Former Stargate Atlantis star David Hewlett (“Rodney McKay”) stars alongside Oscar winner Adrian Brody and Sarah Polley in the upcoming Vincenzo Natali sci-fi horror film Splice.  The film opens nationwide on Friday, June 4.

Splice follows two scientists, Elsa (Polly) and Clive (Brody), who attempt to synthesize a protein-based compound from DNA spliced together DNA from different species.  They finally go against any legal or moral boundaries, splicing together human and animal DNA — creating a new life form which they name “Dren.”

Hewlett plays the bureaucratic Barlow, who is more concerned about profitable gain that comes from splicing then he is about any kind of scientific breakthrough. He can be seen briefly in the trailer, below (at about the 0:22 mark).

Hewlett and director Vincenzo Natali are old friends who went went to high school together. Hewlett appeared in Natali’s 1997 film Cube.  When asked whether this was something David auditioned for Natali said, “Oh, no … I never make David audition. I like to torture David. He is in almost every movie I make.”

Splice filmed in late 2007 and early 2008 with a reported budget of $26 million, and was picked up by Dark Castle Entertainment after strong showings at the Sitges and Sundance Film Festivals. It will be distributed by Warner Bros.

Make sure to check out David in Splice when it hits theaters next month!  Check out the movie’s official Web site at SpliceTheFilm.com.

(Thanks to Tanith for the tip)