When a research team is forced to evacuate their secret base, they find themselves on board a derelict Ancient vessel that is many galaxies away from Earth.
Stranded on the Ancient vessel Destiny, the evacuees from Icarus Base discover that a worn-out life-support system and hull breaches will suffocate them in a matter of hours.
The Destiny suffers a power crisis, putting the lives of the stranded crew in jeopardy when even the emergency reserves run dry. Dr. Rush pushes himself to the breaking point.
With the ship on a collision course, Young conducts a lottery to determine who will escape certain death and try and find a habitable planet with the shuttle.
Severe rationing can't save the Destiny's dwindling water supply, forcing Colonel Young and Lieutenant Scott to seek out drinkable water on a deadly ice planet.
When several of the crew use the communication stones to visit Earth, officials propose a dangerous plan that could return the stranded Destiny crew home.